Allylic C–H oxygenation of unactivated internal olefins by the Cu/azodiformate catalyst system

Abstract Allylic ethers and alcohols are essential structural motifs commonly present in natural products and pharmaceuticals. Direct allylic C–H oxygenation of internal alkenes is one of the most direct methods, bypassing the necessity for an allylic leaving group that is needed in the traditional...

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Bibliographic Details
Main Authors: Le Wang, Yuan She, Jie Xiao, Zi-Hao Li, Shen-Yuan Zhang, Peng-Fei Lian, Tong-Mei Ding, Shu-Yu Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56230-0
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