Associations of aortic and carotid artery health with cerebrovascular markers and cognition in older adults from the Whitehall II imaging study

Associations of aortic and carotid artery health with cerebrovascular markers and cognition in older adults from the Whitehall II imaging study

Abstract Background Cardiovascular disease has been associated with an increased dementia risk, but the underlying mechanisms for this heart-brain link are unclear. This study sought to examine associations between aortic and carotid artery structure with cerebrovascular reactivity (CVR), white matt...

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Main Authors: Georgina Hobden, Graham Reid, Scott T. Chiesa, Congxiyu Wang, Lucy Jobbins, Clare E. Mackay, Alun D. Hughes, Klaus P. Ebmeier, Jemma Pitt, Mika Kivimäki, Archana Singh-Manoux, Sana Suri
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Medicine
Subjects:
Dementia
Carotid
Aorta
Cognition
Ultrasound
Magnetic resonance imaging
Online Access:https://doi.org/10.1186/s12916-025-04105-y
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https://doi.org/10.1186/s12916-025-04105-y

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