Computational phenotyping of brain-behavior dynamics underlying approach-avoidance conflict in major depressive disorder.

Adaptive behavior requires balancing approach and avoidance based on the rewarding and aversive consequences of actions. Imbalances in this evaluation are thought to characterize mood disorders such as major depressive disorder (MDD). We present a novel application of the drift diffusion model (DDM)...

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Bibliographic Details
Main Authors: Mads L Pedersen, Maria Ironside, Ken-Ichi Amemori, Callie L McGrath, Min S Kang, Ann M Graybiel, Diego A Pizzagalli, Michael J Frank
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1008955&type=printable
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