Spatiotemporal dynamics of NF-κB/Dorsal inhibitor IκBα/Cactus in Drosophila blastoderm embryos

Spatiotemporal dynamics of NF-κB/Dorsal inhibitor IκBα/Cactus in Drosophila blastoderm embryos

Summary: The NF-κB/IκBα pathway regulates key cellular processes, including development, immunity, and inflammation. In Drosophila, the homologous Dorsal/Cactus system patterns the dorsoventral axis of the blastoderm embryo. While the inhibitor Cactus has been suggested to play multiple roles in reg...

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Bibliographic Details
Main Authors: Allison E. Schloop, Sharva Vijayakumar Hiremath, Razeen Shaikh, Sadia Siddika Dima, Leslie Lizardo, Amrit Bhakta, Cranos M. Williams, Gregory T. Reeves
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:iScience
Subjects:
Cell biology
Organizational aspects of cell biology
Developmental biology
Mathematical biosciences
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225011150
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