Synergistic anti-cancer effects of metformin and cisplatin on YD-9 oral squamous carcinoma cells via AMPK pathway

Abstract Objective This study evaluated whether hypoglycemic drug metformin enhances the anti-cancer effects of cisplatin in YD-9 cells. Methodology YD-9 cells, derived from oral mucosal squamous cell carcinoma of oral mucosa, were used to assess the combined effects of metformin and cisplatin b...

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Bibliographic Details
Main Authors: Paras Man PRADHAN, Young-Hee LEE, Sungil JANG, Ho-Keun YI
Format: Article
Language:English
Published: University of São Paulo 2025-02-01
Series:Journal of Applied Oral Science
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572025000100407&lng=en&tlng=en
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