The role of Seladelpar in primary biliary cholangitis: a systematic review and meta-analysis

The role of Seladelpar in primary biliary cholangitis: a systematic review and meta-analysis

Abstract Introduction Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease characterized by progressive bile duct destruction, leading to cholestasis and, if untreated, liver failure. Although ursodeoxycholic acid (UDCA) remains the first-line treatment, many patients exhibit an i...

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Main Authors: Taimoor Ashraf, Omar Abunada, Nandlal Seerani, Kashif Ali, Areej Muhammad, Syeda Lamiya Mir, Syed Adil Mir Shah, Muhammad Hassaan, Vikash Kumar, Waseem Abbas, Simran Bajaj, Asfia Qammar, F. N. U. Deepak, Salih Abdella Yusuf
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Gastroenterology
Subjects:
Primary biliary cholangitis
Seladelpar
Liver function
PPAR-δ
Meta-analysis
Online Access:https://doi.org/10.1186/s12876-025-03812-3
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https://doi.org/10.1186/s12876-025-03812-3

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