The PTP1B Inhibitor Trodusquemine (MSI-1436) Improves Glucose Uptake in Equine Metabolic Syndrome Affected Liver through Anti-Inflammatory and Antifibrotic Activity

Background. Hyperactivation of protein tyrosine phosphatase (PTP1B) has been associated with several metabolic malfunctions ranging from insulin resistance, metaflammation, lipotoxicity, and hyperglycaemia. Liver metabolism failure has been proposed as a core element in underlying endocrine disorder...

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Bibliographic Details
Main Authors: Lynda Bourebaba, Anna Serwotka-Suszczak, Nabila Bourebaba, Magdalena Zyzak, Krzysztof Marycz
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.1155/2023/3803056
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