A Cyclic-di-AMP Adjuvanted CPAF Protein Vaccine Is Immunogenic in Swine, but It Fails to Reduce Genital <i>Chlamydia trachomatis</i> Burden

A Cyclic-di-AMP Adjuvanted CPAF Protein Vaccine Is Immunogenic in Swine, but It Fails to Reduce Genital <i>Chlamydia trachomatis</i> Burden

<b>Background/Objectives</b>: <i>Chlamydia trachomatis</i> (<i>Ct</i>) is the leading bacterial cause of sexually transmitted infection globally. If undiagnosed or left untreated, these infections can lead to serious complications such as infertility, ectopic preg...

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Bibliographic Details
Main Authors: Leonie Bettin, Maria Stadler, Christine Unterweger, Maximiliane Dippel, Jonathan M. Harris, Andrea Buzanich-Ladinig, Taylor B. Poston, Toni Darville, Tobias Käser
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Vaccines
Subjects:
<i>Chlamydia trachomatis</i>
vaccination
adjuvant
chlamydial-protease-like activity factor
animal model
pigs
Online Access:https://www.mdpi.com/2076-393X/13/5/468
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