Enhanced in vitro and in vivo antifungal efficacy against Candida albicans of nanostructured lipid carrier loaded with benzyl isothiocyanate extracted from Carica papaya L. seeds

Enhanced in vitro and in vivo antifungal efficacy against Candida albicans of nanostructured lipid carrier loaded with benzyl isothiocyanate extracted from Carica papaya L. seeds

Candida albicans is the most prominent conditional fungal pathogen, which can cause systemic candidiasis when an individual becomes immunocompromised. The widespread and long-term use of azoles like fluconazole (FLC) has led to a significant increase in drug resistance, posing substantial challenges...

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Bibliographic Details
Main Authors: Zelin Zheng, Zijie Li, Mingqi Yu, Xinyi Ma, Jie Gao, Yan Wang, Jinyan Wu, Xiaodan Yu, Yinzheng Ma, Xiaowen He
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Drug Delivery
Subjects:
Papaya seeds
benzyl isothiocyanate
nanostructured lipid carrier
Candida albicans
resistance
systemic candidiasis
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2025.2544687
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https://www.tandfonline.com/doi/10.1080/10717544.2025.2544687

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