Aurora kinase-a expression heterogeneity and potential benefit of combination therapy in prostate adenocarcinoma

BackgroundAurora kinase A (AURKA) is aberrantly expressed in a large number of tumors and promotes tumor progression by regulating the cell cycle, chromosomal instability, and drug resistance. However, its heterogeneous expression and combination therapy benefit in prostate adenocarcinoma (PRAD) is...

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Bibliographic Details
Main Authors: Ru Chen, Qianyi Qiu, Weiting Xie, Jun Lin, Rong Liu, Jianhui Chen, Shaoxing Zhu, Yiming Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1608711/full
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