Comparing benzodiazepine-ketamine and benzodiazepine-fentanyl sedation in phacoemulsification: A double-blind crossover non-inferiority clinical trial (BEKEF study)

Comparing benzodiazepine-ketamine and benzodiazepine-fentanyl sedation in phacoemulsification: A double-blind crossover non-inferiority clinical trial (BEKEF study)

Background: Topical anesthesia for cataract surgery often requires adjunctive sedation to manage intraoperative discomfort and improve patient cooperation. Ketamine and fentanyl, combined with benzodiazepines, are commonly used sedation regimens, but their comparative safety and efficacy in the cata...

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Main Authors: Adriano Cypriano Faneli, Ricardo Danilo Chagas Oliveira, Pablo Amado, Eduardo F. Marback, Rodrigo Amaral Torres, Juliana Fernandes Marback, Larrie Laporte, Caio Vinicius Saito Regatieri, Cristina Muccioli
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Advances in Ophthalmology Practice and Research
Subjects:
Cataract surgery
Sedation
Ketamine
Fentanyl
Phacoemulsification
Online Access:http://www.sciencedirect.com/science/article/pii/S2667376225000162
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