Characterization of TCRβ and IGH Repertoires in the Spleen of Two Chicken Lines with Differential ALV-J Susceptibility Under Normal and Infection Conditions

Characterization of TCRβ and IGH Repertoires in the Spleen of Two Chicken Lines with Differential ALV-J Susceptibility Under Normal and Infection Conditions

This study investigates the immunological factors underlying the differential susceptibility of two chicken strains, E- and M-lines, to avian leukosis virus subgroup J (ALV-J). During the eradication of avian leukosis at a chicken breeder farm in Guangdong, we observed strain-specific differences in...

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Bibliographic Details
Main Authors: Meihuizi Wang, Qihong Zhang, Rongyang Ju, Junliang Xia, Chengxun Xu, Weiding Chen, Xiquan Zhang
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Animals
Subjects:
ALV-J
differential susceptibility
antibody immune response
TCRβ repertoire
IGH repertoire
diversity
Online Access:https://www.mdpi.com/2076-2615/15/3/334
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