MiR-335-5p Escaped from CircKIAA0586 Adsorption Contributes to Mechanical Overloading-Induced Cartilage Degeneration by Targeting Lymphoid-Specific Helicase

MiR-335-5p Escaped from CircKIAA0586 Adsorption Contributes to Mechanical Overloading-Induced Cartilage Degeneration by Targeting Lymphoid-Specific Helicase

Mechanical overload is a critical contributor to cartilage degeneration in osteoarthritis (OA) pathogenesis. Circular RNA (circRNA) is expected to provide a long-lasting therapy for OA. However, the involvement of the circRNA-associated competitive endogenous RNA network in chondrocyte senescence in...

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Main Authors: Haoyu Xie, Yuheng Lu, Jianying Pan, Hua Zeng, Zhicheng Zhang, Jianbin Yin, Jinjian Zhu, Bingsheng Luo, Dong Guo, Chunyu Wu, Chun Zeng, Yan Shao, Xiaochun Bai, Daozhang Cai, Haiyan Zhang
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2025-01-01
Series:Research
Online Access:https://spj.science.org/doi/10.34133/research.0694
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https://spj.science.org/doi/10.34133/research.0694

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