Identification and Cross-Platform Validation of Sparse Molecular Classifiers for Antibody-Mediated and T-Cell–Mediated Rejection After Kidney Transplantation

Identification and Cross-Platform Validation of Sparse Molecular Classifiers for Antibody-Mediated and T-Cell–Mediated Rejection After Kidney Transplantation

Introduction: Molecular classifiers are a promising tool to refine the diagnosis of antibody-mediated rejection (ABMR) and T-cell–mediated rejection (TCMR) after kidney transplantation. Despite this potential, the integration of molecular classifiers in transplant clinics has been slow, in part beca...

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Main Authors: Jasper Callemeyn, Josué Manik Nava-Sedeño, Dany Anglicheau, Jack Beadle, Jan Hinrich Bräsen, Marian C. Clahsen-van Groningen, Iacopo Cristoferi, Henriette de Loor, Andreas Deutsch, Marie Essig, Wilfried Gwinner, Philip F. Halloran, Dennis A. Hesselink, Priyanka Koshy, Dirk Kuypers, Evelyne Lerut, Pierre Marquet, Robert C. Minnee, Candice Roufosse, Ben Sprangers, Amaryllis H. Van Craenenbroeck, Haralampos Hatzikirou, Maarten Naesens
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Kidney International Reports
Subjects:
antibody-mediated rejection
diagnosis
gene expression
kidney transplantation
T-cell–mediated rejection
transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024925001913
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