Analysis Strategy for Identifying the <i>O</i>-Linked Glycan Profile and <i>O</i>-glycosylation Sites on Recombinant Human Follicle Stimulating Hormone-<i>C</i>-terminal Peptide (rhFSH-CTP)

Analysis Strategy for Identifying the <i>O</i>-Linked Glycan Profile and <i>O</i>-glycosylation Sites on Recombinant Human Follicle Stimulating Hormone-<i>C</i>-terminal Peptide (rhFSH-CTP)

<i>O</i>-glycosylation is a common post-translational modification on extracellular and secreted proteins driving biochemical and biophysical interactions at the cell surface. Glycosylation affects drug immunogenicity, efficacy, and clearance, making it a critical attribute of biotherape...

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Bibliographic Details
Main Authors: Xinyue Hu, Yuxing Xiang, Xiaoming Zhang, Yue Sun, Yi Li, Lvyin Wang, Ping Lv, Zhen Long, Chenggang Liang, Jing Li
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molecules
Subjects:
FSH-CTP
<i>O</i>-glycan
<i>O</i>-glycosylation sites
core 1
HCD
ETD
Online Access:https://www.mdpi.com/1420-3049/30/10/2141
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