Jujuboside A improves insomnia by maintaining mitochondrial homeostasis in prefrontal neurons

Jujuboside A improves insomnia by maintaining mitochondrial homeostasis in prefrontal neurons

Objective: Jujuboside A (JB-A) is the major component of Semen Ziziphi Spinosae (SZS), a traditional Chinese herbal medicine used to treat sleep with clinical efficacy. This is the first study to investigate the effects of JB-A on mitochondrial structure and function in the prefrontal cortex of the...

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Bibliographic Details
Main Authors: Zhen Zhang, Xinyue Che, Tingyu Feng, Juntao Zou, Guangpei Chen, Wenping Guo, Chunmei Ma, Haozhe Yuan, Jingying Chen, Xiaowu Xu
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Brain Research Bulletin
Subjects:
Insomnia
Jujuboside A (JB-A)
Mitochondria
Oxidative phosphorylation
Mitochondrial membrane potential (Δψm)
ATP
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025001844
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