An anti-idiotypic single domain antibody as Cry2Aa toxin mimotope and analysis of its binding region through molecular docking

An anti-idiotypic single domain antibody as Cry2Aa toxin mimotope and analysis of its binding region through molecular docking

Abstract Background Anti-idiotypic antibodies have garnered significant attention in biotechnology and immunology due to their unique ability to mimic specific epitopes on target antigens, thereby serving as functional analogues. This property makes them valuable tools for various applications. In t...

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Bibliographic Details
Main Authors: Manman Lin, Guangjie Han, Chuanming Li, Lixin Huang, Qin Liu, Nan Zhang, Yang Xia, Yurong Lu, Xianjin Liu, Yuan Liu, Jian Xu, Johnson Lin
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Biotechnology
Subjects:
Cry2Aa toxin
Anti-idiotypic antibody
Single-domain antibody
Epitopes
Mimotope
Molecular docking
Online Access:https://doi.org/10.1186/s12896-025-01009-w
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https://doi.org/10.1186/s12896-025-01009-w

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