Prospective multicentre cohort trial on acute appendicitis and microbiota, aetiology and effects of antimicrobial treatment: study protocol for the MAPPAC (Microbiology APPendicitis ACuta) trial

Prospective multicentre cohort trial on acute appendicitis and microbiota, aetiology and effects of antimicrobial treatment: study protocol for the MAPPAC (Microbiology APPendicitis ACuta) trial

Introduction Based on the epidemiological and clinical data, acute appendicitis can present either as uncomplicated or complicated. The aetiology of these different appendicitis forms remains unknown. Antibiotic therapy has been shown to be safe, efficient and cost-effective for CT-confirmed uncompl...

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Main Authors: Suvi Sippola, Juha Grönroos, Saija Hurme, Paulina Salminen, Sirpa Jalkanen, Erkki Eerola, Antti J Hakanen, Sanja Vanhatalo, Eveliina Munukka, Harri Marttila, V Sallinen, A Leppäniemi, T Rautio, S Meriläinen, P Nordström, J Laukkarinen, T Rantala, H Savolainen, M Aarnio, A Mattila, J Haijanen, E-L Sävelä, I Imre, H Paajanen, J Rintala, T Pinta, T Sippola, P Böckerman
Format: Article
Language:English
Published: BMJ Publishing Group 2019-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/9/9/e031137.full
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https://bmjopen.bmj.com/content/9/9/e031137.full

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