Recognition and Sequencing of Mutagenic DNA Adduct at Single‐Base Resolution Through Unnatural Base Pair

Recognition and Sequencing of Mutagenic DNA Adduct at Single‐Base Resolution Through Unnatural Base Pair

Abstract DNA lesions are linked to cancer, aging, and various diseases. The recognition and sequencing of special DNA lesions are of great interest but highly challenging. In this paper, an unnatural‐base‐pair‐promoting method for sequencing highly mutagenic ethenodeoxycytidine (εC) DNA lesions that...

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Bibliographic Details
Main Authors: Honglei Wang, Wenchao Tie, Wuyuan Zhu, Shuyuan Wang, Ruzhen Zhang, Jianlin Duan, Bingyu Ye, Anlian Zhu, Lingjun Li
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Advanced Science
Subjects:
3,4‐ethenodeoxycytidine
DNA etheno lesions
sequencing
unnatural base pairs
Online Access:https://doi.org/10.1002/advs.202404622
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https://doi.org/10.1002/advs.202404622

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