LLPS REDIFINE allows the biophysical characterization of multicomponent condensates without tags or labels

Abstract Liquid-liquid phase separation (LLPS) phenomenon plays a vital role in multiple cell biology processes, providing a mechanism to concentrate biomolecules and promote cellular reactions locally. Despite its significance in biology, there is a lack of conventional techniques suitable for stud...

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Bibliographic Details
Main Authors: Mihajlo Novakovic, Yaning Han, Nina C. Kathe, Yinan Ni, Leonidas Emmanouilidis, Frédéric H.-T. Allain
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59759-2
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