Profiling HIV1-host protein–protein interaction networks in patient-derived exosome proteins: impact on pathophysiology and innate immune pathways

Profiling HIV1-host protein–protein interaction networks in patient-derived exosome proteins: impact on pathophysiology and innate immune pathways

Abstract Objectives The objective of this research is to investigate the pathophysiological progression of HIV from acute infection to chronic immunodeficiency (AIDS) and to understand the host’s immunological responses, which are pivotal for elucidating disease aetiology and optimizing antiretrovir...

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Main Authors: Noor Fatima, Mirza Sarwar Baig, Aman Haider Rizvi, Alisha Arzoo, Manu Sharma, Md Shahadab, Aditya Arya, Ayan K. Das, Vineeta Vijay Batra, Keshar Kunja Mohanty, Md Anzar Alam, Ejaj Ahmad, Shakir Ali, Angamuthu Selvapandiyan, Mairaj Ahmed Ansari
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Virology Journal
Subjects:
Human immunodeficiency virus type-1
Innate immune response
Exosomes
Protein–protein interactions
Inflammasome activation
BioGRID version 4.4
Online Access:https://doi.org/10.1186/s12985-025-02717-7
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https://doi.org/10.1186/s12985-025-02717-7

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