Neoadjuvant chemoradiation in older Irish adult patients with oesophageal cancer: a retrospective institutional review of clinical outcomes and hematological toxicity

Neoadjuvant chemoradiation in older Irish adult patients with oesophageal cancer: a retrospective institutional review of clinical outcomes and hematological toxicity

Abstract Background and objectives Neoadjuvant chemo-radiotherapy improves survival compared with surgery alone in locally advanced oesophageal cancer. In the Chemo-Radiotherapy for Oesophageal cancer followed by Surgery Study (CROSS) randomised controlled trial (RCT), the median age was 60. However...

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Main Authors: Ronan Andrew McLaughlin, David McMahon, Christopher Cluxton, Orla Meave Fitzpatrick, Michael Conroy, Majid Almeraikhi, Humaid Alkaabi, Fianait Bligh, Brian O’Neill, Mayilone Arumugasamy, William Robb, Oscar Seamus Breathnach, William Grogan, Bryan T. Hennessy, Adrian Murphy, Jarsuhka Naidoo, Megan Greally, Kathleen Bennett, Patrick G Morris
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Cancer
Subjects:
Ireland
Older adult
Oesophageal cancer
Chemoradiation
Oesophagostomy surgery
Tolerability
Online Access:https://doi.org/10.1186/s12885-025-14055-6
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https://doi.org/10.1186/s12885-025-14055-6

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