METTL14 mediates the m6A methylation of miR-29a-3p, thereby activating the MAP2K6 signaling pathway and exacerbating the inflammatory response associated with spinal tuberculosis

METTL14 mediates the m6A methylation of miR-29a-3p, thereby activating the MAP2K6 signaling pathway and exacerbating the inflammatory response associated with spinal tuberculosis

Abstract Background Spinal Tuberculosis (STB) constitutes a common form of tuberculosis and is more widespread in developing countries. Not only is it one of the principal causes of spinal deformity but also it may trigger severe neurological impairments, thereby significantly influencing the qualit...

Full description

Saved in:
Bibliographic Details
Main Authors: Lijun Feng, Mengqi Zhu, Xu Zhang, Ningkui Niu, Zhiyun Shi
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Spinal tuberculosis
METTL14
miR-29a-3p
MAP2K6
Inflammatory response
Online Access:https://doi.org/10.1186/s13018-025-06037-y
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s13018-025-06037-y

Similar Items