Hyperglycemia-induced oxidative stress exacerbates mitochondrial apoptosis damage to cochlear stria vascularis pericytes via the ROS-mediated Bcl-2/CytC/AIF pathway

Objectives: Diabetes is closely linked to hearing loss, yet the exact mechanisms remain unclear. Cochlear stria vascularis and pericytes (PCs) are crucial for hearing. This study investigates whether high glucose induces apoptosis in the cochlear stria vascularis and pericytes via elevated ROS level...

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Bibliographic Details
Main Authors: Tian-feng Shi, Zan Zhou, Wen-jun Jiang, Tian-lan Huang, Jun-qiang Si, Li Li
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Redox Report
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Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2024.2382943
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