Comparative metabolomics of acetylcholinesterase and α-glucosidase inhibitors in pericarp of Garcinia mangostana L.

Comparative metabolomics of acetylcholinesterase and α-glucosidase inhibitors in pericarp of Garcinia mangostana L.

Abstract Background Mangosteen (Garcinia mangostana L.) pericarp extract has demonstrated potential against Alzheimer’s disease (AD) and diabetes mellitus (DM). This study introduces a rapid dereplication and comparative approach to identify and characterize acetylcholinesterase (AChE) and α-glucosi...

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Main Authors: Yun-Han Wang, Ta-Wei Liu, Sui-Wen Hsiao, Man-Hsiu Chu, Tzong-Huei Lee, Su-Jung Hsu, Shih Yin Chen, Ching-Kuo Lee
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:Botanical Studies
Subjects:
Mangosteen (Garciniaman gostana L)
Acetylcholinesterase
α-glucosidase
Dereplication
Comparative metabolomics
Online Access:https://doi.org/10.1186/s40529-025-00460-4
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https://doi.org/10.1186/s40529-025-00460-4

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