Transposon insertion sequencing reveals novel hypermutator genes in Acinetobacter baumannii

Transposon insertion sequencing reveals novel hypermutator genes in Acinetobacter baumannii

ABSTRACT Mutation rates in bacteria are an important determinant of adaptation to new environments and success in different niches. In some bacterial pathogens, “hypermutator” variants—most often associated with mutations in components of the DNA mismatch repair system—are associated with increased...

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Bibliographic Details
Main Authors: Francesca L. Short, Ram Maharjan, Liping Li, Nusrat Afrin, Natasha Delgado, Christine J. Boinett, Julian Parkhill, Amy K. Cain, Ian T. Paulsen
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:mBio
Subjects:
hypermutator
tn-seq
tradis
mutation rate
Acinetobacter
Online Access:https://journals.asm.org/doi/10.1128/mbio.00966-25
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https://journals.asm.org/doi/10.1128/mbio.00966-25

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