Platelet-activating factor acetylhydrolase and haemophagocytosis in the sepsis syndrome

Sepsis syndrome (SS) is associated with depressed PAF acetylhydrolase, the enzyme responsible for the degradation of platelet activating factor. PAF acetylhydrolase is in a large part produced by macrophages, whose inadequate activation with haemophagocytosis is frequent in patients with SS.

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Bibliographic Details
Main Authors: Franck Trimoreau, Bruno François, Arnaud Desachy, Arnaud Besse, Philippe Vignon, Yves Denizot
Format: Article
Language:English
Published: Wiley 2000-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629350020002921
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