Autonomic brain functioning and age-related health concerns
The autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signa...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Current Research in Physiology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2665944124000075 |
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| author | Amjad Z. Alrosan Ghaith B. Heilat Khaled Alrosan Abrar A. Aleikish Aya N. Rabbaa Aseel M. Shakhatreh Ehab M. Alshalout Enaam M.A. Al Momany |
| author_facet | Amjad Z. Alrosan Ghaith B. Heilat Khaled Alrosan Abrar A. Aleikish Aya N. Rabbaa Aseel M. Shakhatreh Ehab M. Alshalout Enaam M.A. Al Momany |
| author_sort | Amjad Z. Alrosan |
| collection | DOAJ |
| description | The autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the most well-known alterations in the ANS associated with health issues, including cardiovascular diseases and cognitive decline. The inability to perform fundamental activities of daily living and compromising the physiological reactivity or motivational responses of older adults to moving toward or away from specific environmental stimuli are significant negative consequences of chronic and geriatric conditions that pose grave threats to autonomy, health, and well-being. The most updated research has investigated the associations between the action responsiveness of older adults and the maintenance of their physiological and physical health or the development of mental and physical health problems. Once autonomic dysfunction may significantly influence the development of different age-related diseases, including ischemic stroke, cardiovascular disease, and autoimmune diseases, this review aimed to assess the relationship between aging and autonomic functions. The review explored how motivational responses, physiological reactivity, cognitive processes, and lifelong developmental changes associated with aging impact the ANS and contribute to the emergence of health problems. |
| format | Article |
| id | doaj-art-53e319ebe7e3429db7bbce700879b53a |
| institution | Kabale University |
| issn | 2665-9441 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Current Research in Physiology |
| spelling | doaj-art-53e319ebe7e3429db7bbce700879b53a2024-12-03T04:30:00ZengElsevierCurrent Research in Physiology2665-94412024-01-017100123Autonomic brain functioning and age-related health concernsAmjad Z. Alrosan0Ghaith B. Heilat1Khaled Alrosan2Abrar A. Aleikish3Aya N. Rabbaa4Aseel M. Shakhatreh5Ehab M. Alshalout6Enaam M.A. Al Momany7Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa, 13133, Jordan; Corresponding author. 15 Damascus International Road 453J+5C5, 25 km Northeast of Amman, Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa, 13133, Jordan.Department of General Surgery and Urology, Faculty of Medicine, The Jordan University of Science and Technology, Irbid, 22110, JordanDepartment of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa, 13133, JordanMaster of Pharmacology, Department of Pharmacology, Faculty of Medicine, The Jordan University of Science and Technology, Irbid, 22110, JordanFaculty of Pharmaceutical Sciences, The Hashemite University, Zarqa, 13133, JordanDepartment of Biochemistry and Molecular Biology, Faculty of Medicine, The Jordan University of Science and Technology, Irbid, 22110, JordanFaculty of Pharmaceutical Sciences, The Hashemite University, Zarqa, 13133, JordanDepartment of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa, 13133, JordanThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the most well-known alterations in the ANS associated with health issues, including cardiovascular diseases and cognitive decline. The inability to perform fundamental activities of daily living and compromising the physiological reactivity or motivational responses of older adults to moving toward or away from specific environmental stimuli are significant negative consequences of chronic and geriatric conditions that pose grave threats to autonomy, health, and well-being. The most updated research has investigated the associations between the action responsiveness of older adults and the maintenance of their physiological and physical health or the development of mental and physical health problems. Once autonomic dysfunction may significantly influence the development of different age-related diseases, including ischemic stroke, cardiovascular disease, and autoimmune diseases, this review aimed to assess the relationship between aging and autonomic functions. The review explored how motivational responses, physiological reactivity, cognitive processes, and lifelong developmental changes associated with aging impact the ANS and contribute to the emergence of health problems.http://www.sciencedirect.com/science/article/pii/S2665944124000075Autonomic nervous systemAgingHealthPhysiological reactivityStimulus |
| spellingShingle | Amjad Z. Alrosan Ghaith B. Heilat Khaled Alrosan Abrar A. Aleikish Aya N. Rabbaa Aseel M. Shakhatreh Ehab M. Alshalout Enaam M.A. Al Momany Autonomic brain functioning and age-related health concerns Current Research in Physiology Autonomic nervous system Aging Health Physiological reactivity Stimulus |
| title | Autonomic brain functioning and age-related health concerns |
| title_full | Autonomic brain functioning and age-related health concerns |
| title_fullStr | Autonomic brain functioning and age-related health concerns |
| title_full_unstemmed | Autonomic brain functioning and age-related health concerns |
| title_short | Autonomic brain functioning and age-related health concerns |
| title_sort | autonomic brain functioning and age related health concerns |
| topic | Autonomic nervous system Aging Health Physiological reactivity Stimulus |
| url | http://www.sciencedirect.com/science/article/pii/S2665944124000075 |
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