Retrotransposition-competent L1s are increased in the genomes of individuals with amyotrophic lateral sclerosis

An individual’s genetics contributes to their risk of developing amyotrophic lateral sclerosis (ALS); however, there is still a large proportion of the heritability of ALS to be understood. Part of this missing heritability may lie in complex variants, such as the long interspersed element 1 (L1) re...

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Bibliographic Details
Main Authors: Abigail L. Pfaff, Sulev Kõks
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Experimental Biology and Medicine
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Online Access:https://www.ebm-journal.org/articles/10.3389/ebm.2025.10575/full
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