A pharmacovigilance study of thromboembolism events associated with vascular endothelial growth factor receptor tyrosine kinase inhibitors based on FAERS database

A pharmacovigilance study of thromboembolism events associated with vascular endothelial growth factor receptor tyrosine kinase inhibitors based on FAERS database

Abstract Vascular endothelial growth factor receptor tyrosine kinase inhibitors (VEGFR-TKIs) represent a class of targeted drugs that have changed the cancer therapy landscape. However, the anti-angiogenic effect of VEGFR-TKIs significantly increase the incidence of cardiovascular adverse events (AE...

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Bibliographic Details
Main Authors: Zongwei Tang, Haichi Song, Lingyun Pan, Min Zhang, Siyu Li, Wenrui Li, Wanyi Chen, Xiaoxiao Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Vascular endothelial growth factor receptor tyrosine kinase inhibitor
Thromboembolic event
Pharmacovigilance
FAERS
Online Access:https://doi.org/10.1038/s41598-025-11067-x
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https://doi.org/10.1038/s41598-025-11067-x

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