Rapid emergence of dolutegravir resistance on second-line dolutegravir-based ART
The integrase strand transfer inhibitor, dolutegravir (DTG), is widely used in first- and second-line antiretroviral therapy (ART) regimens in South Africa. We describe an adult with virological failure on second-line tenofovir/lamivudine/dolutegravir (TLD2) and rapid emergence of DTG resistance wit...
Saved in:
| Main Authors: | Kirusha Naidoo, Richard J. Lessells, Jienchi Dorward, Mahomed Y.S. Moosa, Yukteshwar Sookrajh, Pravi Moodley, Paul K. Drain, Nigel Garrett |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
AOSIS
2025-04-01
|
| Series: | Southern African Journal of HIV Medicine |
| Subjects: | |
| Online Access: | https://sajhivmed.org.za/index.php/hivmed/article/view/1701 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Longer-term virologic outcomes on tenofovir-lamivudine-dolutegravir in second-line ART
by: Jennifer K. van Heerden, et al.
Published: (2025-04-01) -
HIV Drug Resistance Profile in Clients Experiencing Treatment Failure After the Transition to a Dolutegravir-Based First-Line Antiretroviral Treatment Regimen in Mozambique
by: Nalia Ismael, et al.
Published: (2025-01-01) -
Safe Switch to an Oral Two‐Drug Regimen Based on Dolutegravir in People With Vertically Acquired HIV‐1: An Observational Multicenter Study
by: Giulia Meraviglia, et al.
Published: (2025-07-01) -
First Reported Case of Integrase Strand Transfer Inhibitor Resistance in Suriname: Unusual Drug Resistance Mutations Following Exposure to Dolutegravir
by: Rachel C. Sno, et al.
Published: (2025-02-01) -
HIV drug resistance in children and adolescents on NNRTI-based antiretroviral therapy and subsequent virologic response to dolutegravir-based regimens in Ghana
by: Adwoa K.A Afrane, et al.
Published: (2025-07-01)