MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer.

MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer.

The identification of new biomarkers for preneoplastic pancreatic lesions (PanINs, IPMNs) and early pancreatic ductal adenocarcinoma (PDAC) is crucial due to the diseases high mortality rate upon late detection. To address this task we used the novel technique of matrix-assisted laser desorption/ion...

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Main Authors: Barbara M Grüner, Hannes Hahne, Pawel K Mazur, Marija Trajkovic-Arsic, Stefan Maier, Irene Esposito, Evdokia Kalideris, Christoph W Michalski, Jörg Kleeff, Sandra Rauser, Roland M Schmid, Bernhard Küster, Axel Walch, Jens T Siveke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0039424&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0039424&type=printable

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