Evaluation of encapsulated proteolytic enzymes from white shrimp (Litopenaeus vannamei) hepatopancreas for potential supplementation in tilapia feed

This study aimed to evaluate the extraction, semi-purification, encapsulation, and release of proteolytic enzymes from the hepatopancreas of white shrimp (Litopenaeus vannamei) for potential inclusion in pelleted feed for tilapia. Proteases were extracted using hydrophobic interaction chromatography...

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Main Authors: Pablo Sergio Osuna-Amarillas, Kenia Yamileth Medina-Rivera, Martha Elisa Rivas-Vega, Francisco Javier Cinco-Moroyoqui, Octavio Cota-Arriola, Wilfrido Torres-Arriola, Norma Aurora Stephens-Camacho, Anselmo Miranda-Baeza
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Food Chemistry Advances
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772753X25000097
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author Pablo Sergio Osuna-Amarillas
Kenia Yamileth Medina-Rivera
Martha Elisa Rivas-Vega
Francisco Javier Cinco-Moroyoqui
Octavio Cota-Arriola
Wilfrido Torres-Arriola
Norma Aurora Stephens-Camacho
Anselmo Miranda-Baeza
author_facet Pablo Sergio Osuna-Amarillas
Kenia Yamileth Medina-Rivera
Martha Elisa Rivas-Vega
Francisco Javier Cinco-Moroyoqui
Octavio Cota-Arriola
Wilfrido Torres-Arriola
Norma Aurora Stephens-Camacho
Anselmo Miranda-Baeza
author_sort Pablo Sergio Osuna-Amarillas
collection DOAJ
description This study aimed to evaluate the extraction, semi-purification, encapsulation, and release of proteolytic enzymes from the hepatopancreas of white shrimp (Litopenaeus vannamei) for potential inclusion in pelleted feed for tilapia. Proteases were extracted using hydrophobic interaction chromatography, yielding a semi-purified shrimp hepatopancreas extract (SPESH). SDS-PAGE analysis identified four distinct protein bands and the optimal conditions for enzyme activity were determined across a range of temperatures (0–100 °C) and pH levels (4–11). Inhibition assays revealed the presence of serine proteases, primarily trypsin-type enzymes, alongside aspartic and cysteine proteases. SPESH exhibited maximum proteolytic activity at 40 °C and pH 9. Proteolytic activity from the sodium alginate capsules was observed 30 min after encapsulation release testing, with a stable trend up to 120 min. Over the 0–16 days storage period, the proteolytic activity of capsules incubated for 60 min (36.3 ± 2.80 to 38.4 ± 1.21 AU) and 120 min (45.4 ± 1.40 to 47.8 ± 0.28 AU) prevailed stable with no significant differences (P < 0.05), indicating consistent enzyme release. The encapsulation method allowed a gradual release of enzymes at pH conditions representative of the Nile tilapia (Oreochromis niloticus) digestive tract, supporting its potential for controlled delivery and enzyme supplementation in feed.
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spelling doaj-art-5351b0eae80f47c0891c324e4d8edc342025-08-20T02:52:20ZengElsevierFood Chemistry Advances2772-753X2025-03-01610089310.1016/j.focha.2025.100893Evaluation of encapsulated proteolytic enzymes from white shrimp (Litopenaeus vannamei) hepatopancreas for potential supplementation in tilapia feedPablo Sergio Osuna-Amarillas0Kenia Yamileth Medina-Rivera1Martha Elisa Rivas-Vega2Francisco Javier Cinco-Moroyoqui3Octavio Cota-Arriola4Wilfrido Torres-Arriola5Norma Aurora Stephens-Camacho6Anselmo Miranda-Baeza7Laboratorio de Tecnologías de cultivo de organismos acuáticos. Universidad Estatal de Sonora (UES), Navojoa, Sonora, 85875, MexicoMaestría en Producción y Gestión de Negocios Agropecuarios. Universidad Estatal de Sonora (UES), Navojoa, Sonora, 85875, MexicoLaboratorio de Tecnologías de cultivo de organismos acuáticos. Universidad Estatal de Sonora (UES), Navojoa, Sonora, 85875, MexicoDepartamento de Investigación y Posgrado en Alimentos (DIPA). Universidad de Sonora (UNISON), Hermosillo, Sonora, 83000, MexicoIngeniería Ambiental, Unidad Académica Hermosillo. Universidad Estatal de Sonora (UES). Hermosillo, Sonora, 83100, MexicoDepartamento de Investigación y Posgrado en Alimentos (DIPA). Universidad de Sonora (UNISON), Hermosillo, Sonora, 83000, MexicoNutrición Humana, Universidad Estatal de Sonora (UES). Navojoa, Sonora, 85875, MexicoLaboratorio de Tecnologías de cultivo de organismos acuáticos. Universidad Estatal de Sonora (UES), Navojoa, Sonora, 85875, Mexico; Corresponding author at: Laboratorio de Tecnologías de cultivo de organismos acuáticos. Universidad Estatal de Sonora (UES), Navojoa, Sonora, 85875, México.This study aimed to evaluate the extraction, semi-purification, encapsulation, and release of proteolytic enzymes from the hepatopancreas of white shrimp (Litopenaeus vannamei) for potential inclusion in pelleted feed for tilapia. Proteases were extracted using hydrophobic interaction chromatography, yielding a semi-purified shrimp hepatopancreas extract (SPESH). SDS-PAGE analysis identified four distinct protein bands and the optimal conditions for enzyme activity were determined across a range of temperatures (0–100 °C) and pH levels (4–11). Inhibition assays revealed the presence of serine proteases, primarily trypsin-type enzymes, alongside aspartic and cysteine proteases. SPESH exhibited maximum proteolytic activity at 40 °C and pH 9. Proteolytic activity from the sodium alginate capsules was observed 30 min after encapsulation release testing, with a stable trend up to 120 min. Over the 0–16 days storage period, the proteolytic activity of capsules incubated for 60 min (36.3 ± 2.80 to 38.4 ± 1.21 AU) and 120 min (45.4 ± 1.40 to 47.8 ± 0.28 AU) prevailed stable with no significant differences (P < 0.05), indicating consistent enzyme release. The encapsulation method allowed a gradual release of enzymes at pH conditions representative of the Nile tilapia (Oreochromis niloticus) digestive tract, supporting its potential for controlled delivery and enzyme supplementation in feed.http://www.sciencedirect.com/science/article/pii/S2772753X25000097Enzyme encapsulationDigestive proteasesProteolytic activitySodium alginate capsulesShrimp waste
spellingShingle Pablo Sergio Osuna-Amarillas
Kenia Yamileth Medina-Rivera
Martha Elisa Rivas-Vega
Francisco Javier Cinco-Moroyoqui
Octavio Cota-Arriola
Wilfrido Torres-Arriola
Norma Aurora Stephens-Camacho
Anselmo Miranda-Baeza
Evaluation of encapsulated proteolytic enzymes from white shrimp (Litopenaeus vannamei) hepatopancreas for potential supplementation in tilapia feed
Food Chemistry Advances
Enzyme encapsulation
Digestive proteases
Proteolytic activity
Sodium alginate capsules
Shrimp waste
title Evaluation of encapsulated proteolytic enzymes from white shrimp (Litopenaeus vannamei) hepatopancreas for potential supplementation in tilapia feed
title_full Evaluation of encapsulated proteolytic enzymes from white shrimp (Litopenaeus vannamei) hepatopancreas for potential supplementation in tilapia feed
title_fullStr Evaluation of encapsulated proteolytic enzymes from white shrimp (Litopenaeus vannamei) hepatopancreas for potential supplementation in tilapia feed
title_full_unstemmed Evaluation of encapsulated proteolytic enzymes from white shrimp (Litopenaeus vannamei) hepatopancreas for potential supplementation in tilapia feed
title_short Evaluation of encapsulated proteolytic enzymes from white shrimp (Litopenaeus vannamei) hepatopancreas for potential supplementation in tilapia feed
title_sort evaluation of encapsulated proteolytic enzymes from white shrimp litopenaeus vannamei hepatopancreas for potential supplementation in tilapia feed
topic Enzyme encapsulation
Digestive proteases
Proteolytic activity
Sodium alginate capsules
Shrimp waste
url http://www.sciencedirect.com/science/article/pii/S2772753X25000097
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