PCSK9 promotes progression of anaplastic thyroid cancer through E-cadherin endocytosis

Abstract Although anaplastic thyroid cancer (ATC) constitutes only 1–2% of all thyroid malignancies, it is associated with an exceptionally high mortality rate, accounting for 14–39% of thyroid cancer-related deaths. In this study, we identified the critical role of Proprotein Convertase Subtilisin/...

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Bibliographic Details
Main Authors: Yu Zhang, Wei Su, Xiaoyu Ji, Zhou Yang, Qing Guan, Yuanxin Pang, Linkun Zhong, Yu Wang, Jun Xiang
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07690-1
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