MiR-493-5p functions as a tumour suppressor in head and neck squamous cell carcinoma progression by targeting HIF-1α

MiR-493-5p functions as a tumour suppressor in head and neck squamous cell carcinoma progression by targeting HIF-1α

Abstract Background Head and neck squamous cell carcinoma (HNSCC) demonstrates insidious onset, high prevalence, and low 5-year overall survival rate. While downregulation of miR-493-5p is implicated in the development of various cancers, its role in HNSCC remains unclear. Here, we explored the asso...

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Bibliographic Details
Main Authors: Jiahui Liu, Ruxian Tian, Xi Chen, Qing Song, Caiyu Sun, Dongxian Li, Yuhui Fang, Shijun Lv, Yumei Li, Xicheng Song
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
Head and neck squamous cell carcinoma
MiR-493-5p
HIF-1α
Proliferation
Migration
Online Access:https://doi.org/10.1007/s12672-025-02690-1
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https://doi.org/10.1007/s12672-025-02690-1

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