Molecular profile of salivary gland tumors: discovering new targets for therapy

Molecular profile of salivary gland tumors: discovering new targets for therapy

Introduction. Due to variety of morphological subtypes and poor clinical response, comprehensive molecular profiling for salivary gland cancers become a part of treatment strategy for chemotherapy-resistant cases. Tumors of the salivary glands include more than 20 histological types distinguished by...

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Bibliographic Details
Main Authors: A. V. Ignatova, Yu.  V. Alymov, I.  S. Romanov
Format: Article
Language:Russian
Published: ABV-press 2024-12-01
Series:Опухоли головы и шеи
Subjects:
molecular profiling
salivary gland cancer
androgen receptor
epidermal growth factor receptor type 2
epidermal growth factor receptor
programmed cell death receptor
cps
сd117
estrogen receptor
progesterone receptor
pan-trk
<i>alk</i>
<i>braf</i>
<i>erbb2</i>
<i>kit</i>
<i>met</i>
<i>ret</i>
<i>ros1</i>
<i>smo</i>
<i>ar</i>
<i>hras</i>
<i>pik3ca</i>
<i>pdgfra</i>
<i>ntrk1-3</i>
new-generation sequencing
immunohistochemical examination
targeted therapy
Online Access:https://ogsh.abvpress.ru/jour/article/view/1020
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