Efficacy and safety of mitoxantrone hydrochloride liposome-containing regimens in treating refractory/relapsed acute myeloid leukemia

Efficacy and safety of mitoxantrone hydrochloride liposome-containing regimens in treating refractory/relapsed acute myeloid leukemia

Abstract Background Despite the poor prognosis for patients with relapsed/refractory (R/R) acute myeloid leukemia (AML), an optimal treatment strategy remains undefined. Mitoxantrone (MIT) is widely used to treat R/R AML. Methods This prospective, single-center, open-label study assessed the efficac...

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Main Authors: Ni Lu, Li Liu, Yigeng Cao, Rongli Zhang, Weihua Zhai, Xin Chen, Qiaoling Ma, Donglin Yang, Aiming Pang, Jialin Wei, Yi He, Sizhou Feng, Mingzhe Han, Erlie Jiang
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
Acute myeloid leukemia
Relapsed/refractory acute myeloid leukemia
Mitoxantrone hydrochloride liposome
Allogeneic hematopoietic stem cell transplantation
Composite complete remission
Online Access:https://doi.org/10.1007/s12672-025-02526-y
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https://doi.org/10.1007/s12672-025-02526-y

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