Very‐low‐carbohydrate diet enhances human T‐cell immunity through immunometabolic reprogramming

Very‐low‐carbohydrate diet enhances human T‐cell immunity through immunometabolic reprogramming

Abstract Very‐low‐carbohydrate diet triggers the endogenous production of ketone bodies as alternative energy substrates. There are as yet unproven assumptions that ketone bodies positively affect human immunity. We have investigated this topic in an in vitro model using primary human T cells and in...

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Main Authors: Simon Hirschberger, Gabriele Strauß, David Effinger, Xaver Marstaller, Alicia Ferstl, Martin B Müller, Tingting Wu, Max Hübner, Tim Rahmel, Hannah Mascolo, Nicole Exner, Julia Heß, Friedrich W Kreth, Kristian Unger, Simone Kreth
Format: Article
Language:English
Published: Springer Nature 2021-06-01
Series:EMBO Molecular Medicine
Subjects:
immunometabolism
ketogenic diet
metabolic therapy
nutritional intervention
T‐cell immunity
Online Access:https://doi.org/10.15252/emmm.202114323
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https://doi.org/10.15252/emmm.202114323

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