Elevated plasma level of PAI-1 is associated with severe COVID-19

Elevated plasma level of PAI-1 is associated with severe COVID-19

Abstract Evidence indicates endothelial dysfunction in severe coronavirus disease (COVID-19). Plasminogen activator inhibitor-1 (PAI-1) is a marker of endothelial injury and could be a prognostic marker for COVID-19-related hospitalization and outcomes. The association between PAI-1 levels and the s...

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Bibliographic Details
Main Authors: Susumu Fukahori, Yurika Kawazoe, Jung Yeon Han, Narasaiah Kolliputi, Kaitlyn Lezama, Rajesh Kumar, Hiroshi Mukae, Richard F. Lockey, Iset Medina Vera, Kami Kim, Seong H. Cho
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
COVID-19
PAI-1
Biomarker
Prognostic factor
Online Access:https://doi.org/10.1038/s41598-025-06517-5
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https://doi.org/10.1038/s41598-025-06517-5

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