Ligand‐dependent responses of the ErbB signaling network: experimental and modeling analyses
Abstract Deregulation of ErbB signaling plays a key role in the progression of multiple human cancers. To help understand ErbB signaling quantitatively, in this work we combine traditional experiments with computational modeling, building a model that describes how stimulation of all four ErbB recep...
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| Main Authors: | Marc R Birtwistle, Mariko Hatakeyama, Noriko Yumoto, Babatunde A Ogunnaike, Jan B Hoek, Boris N Kholodenko |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2007-11-01
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| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/msb4100188 |
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