Evaluating the role of lipopolysaccharides in the joint: fibronectin as a novel protective mechanism

Evaluating the role of lipopolysaccharides in the joint: fibronectin as a novel protective mechanism

Objective To investigate the presence and bioactivity of lipopolysaccharides (LPS) in synovial fluid (SF) of osteoarthritis (OA) patients and elucidate mechanisms modulating their inflammatory potential.Methods SF samples from 56 OA, 7 rheumatoid arthritis and 39 trauma patients were analysed for LP...

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Main Authors: Kari K Eklund, Caroline Ospelt, Thomas Rauer, Rodolfo Gómez, Hans-Christoph Pape, Kajetana Bevc, Shipin Zhang, Andres Pazos-Perez, Ana Alonso-Perez, David Fercher, Sami Kauppinen, Tuomas Frondelius, Valentino Bruhin, Gian Salzmann, Mikko Arttu Jalmari Finnilä, Marcy Zenobi Wong, Goncalo Barreto
Format: Article
Language:English
Published: BMJ Publishing Group 2025-07-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/11/3/e005622.full
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https://rmdopen.bmj.com/content/11/3/e005622.full

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