Black Pepper’s Anti-Aging and Chemoprevention Properties: A Review

The possible uses of black pepper, a common spice used for cooking, have been expanded. Despite countless studies on its advantageous biological effects, it would be difficult to determine its effectiveness as an anti-aging and chemo-preventive medication. Piperine, chavicine, caryophyllene, and sab...

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Main Author: Endah
Format: Article
Language:English
Published: LPPT Universitas Gadjah Mada 2023-12-01
Series:Journal of Food and Pharmaceutical Sciences
Subjects:
Online Access:https://jurnal.ugm.ac.id/v3/JFPS/article/view/7100/3310
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author Endah
author_facet Endah
author_sort Endah
collection DOAJ
description The possible uses of black pepper, a common spice used for cooking, have been expanded. Despite countless studies on its advantageous biological effects, it would be difficult to determine its effectiveness as an anti-aging and chemo-preventive medication. Piperine, chavicine, caryophyllene, and sabinene are a few examples of black pepper components that exhibit pharmacological characteristics. This article reviews black pepper's main ingredients and discusses how effective it is at preventing aging and cancer. Using Google Scholar, PubMed, and Medline for our electronic research, we screened pertinent papers from scientific journals. To help with the explanation in the narrative, all the data was compiled and summarized into tables and graphs. Overall, the anti-aging properties of black pepper and its constituents are exhibited through several pathways, including senescence prevention, antioxidant protection, control of ROS levels, and the inhibition of aging-related enzymes. Additionally, cell cycle regulation, antiangiogenic and anti-metastatic action, apoptosis induction, and the suppression of carcinogenesis are some of the mechanisms utilized in cancer prevention activities. It has been shown to have synergistic effects on several cancer cells when combined with doxorubicin. According to these studies, black pepper could be considered for development as an anti-aging and chemo-preventive agent.
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spelling doaj-art-52dfd535ad2742b8b0df96ae52a162122025-01-24T08:04:18ZengLPPT Universitas Gadjah MadaJournal of Food and Pharmaceutical Sciences2089-72002339-09482023-12-0111390091610.22146/jfps.7100Black Pepper’s Anti-Aging and Chemoprevention Properties: A ReviewEndah0Department of Biomedical Engineering, Sumatera Institute of Technology, Lampung, IndonesiaThe possible uses of black pepper, a common spice used for cooking, have been expanded. Despite countless studies on its advantageous biological effects, it would be difficult to determine its effectiveness as an anti-aging and chemo-preventive medication. Piperine, chavicine, caryophyllene, and sabinene are a few examples of black pepper components that exhibit pharmacological characteristics. This article reviews black pepper's main ingredients and discusses how effective it is at preventing aging and cancer. Using Google Scholar, PubMed, and Medline for our electronic research, we screened pertinent papers from scientific journals. To help with the explanation in the narrative, all the data was compiled and summarized into tables and graphs. Overall, the anti-aging properties of black pepper and its constituents are exhibited through several pathways, including senescence prevention, antioxidant protection, control of ROS levels, and the inhibition of aging-related enzymes. Additionally, cell cycle regulation, antiangiogenic and anti-metastatic action, apoptosis induction, and the suppression of carcinogenesis are some of the mechanisms utilized in cancer prevention activities. It has been shown to have synergistic effects on several cancer cells when combined with doxorubicin. According to these studies, black pepper could be considered for development as an anti-aging and chemo-preventive agent.https://jurnal.ugm.ac.id/v3/JFPS/article/view/7100/3310piperinecanceranti-agingchemopreventionblack pepper
spellingShingle Endah
Black Pepper’s Anti-Aging and Chemoprevention Properties: A Review
Journal of Food and Pharmaceutical Sciences
piperine
cancer
anti-aging
chemoprevention
black pepper
title Black Pepper’s Anti-Aging and Chemoprevention Properties: A Review
title_full Black Pepper’s Anti-Aging and Chemoprevention Properties: A Review
title_fullStr Black Pepper’s Anti-Aging and Chemoprevention Properties: A Review
title_full_unstemmed Black Pepper’s Anti-Aging and Chemoprevention Properties: A Review
title_short Black Pepper’s Anti-Aging and Chemoprevention Properties: A Review
title_sort black pepper s anti aging and chemoprevention properties a review
topic piperine
cancer
anti-aging
chemoprevention
black pepper
url https://jurnal.ugm.ac.id/v3/JFPS/article/view/7100/3310
work_keys_str_mv AT endah blackpeppersantiagingandchemopreventionpropertiesareview