Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development.

Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development.

An age-dependent association between variation at the FTO locus and BMI in children has been suggested. We meta-analyzed associations between the FTO locus (rs9939609) and BMI in samples, aged from early infancy to 13 years, from 8 cohorts of European ancestry. We found a positive association betwee...

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Main Authors: Ulla Sovio, Dennis O Mook-Kanamori, Nicole M Warrington, Robert Lawrence, Laurent Briollais, Colin N A Palmer, Joanne Cecil, Johanna K Sandling, Ann-Christine Syvänen, Marika Kaakinen, Lawrie J Beilin, Iona Y Millwood, Amanda J Bennett, Jaana Laitinen, Anneli Pouta, John Molitor, George Davey Smith, Yoav Ben-Shlomo, Vincent W V Jaddoe, Lyle J Palmer, Craig E Pennell, Tim J Cole, Mark I McCarthy, Marjo-Riitta Järvelin, Nicholas J Timpson, Early Growth Genetics Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1001307
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https://doi.org/10.1371/journal.pgen.1001307

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