Sequential SARS-CoV-2 mRNA Vaccination Induces Anti-Idiotype (Anti-ACE2) Antibodies in K18 Human ACE2 Transgenic Mice

Background/Objectives: Novel mRNA vaccines have been successfully utilized to curtail the SARS-CoV-2 pandemic. However, the immunology underlying CoV2 vaccinations, particularly with repeated boosting, has not been properly characterized due to limitations in the preclinical modeling of SARS-CoV-2 i...

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Bibliographic Details
Main Authors: Craig P. Collins, Christian Herzog, Logan V. Vick, Ryan Nielsen, Yanping Izak Harville, Dan L. Longo, John M. Arthur, William J. Murphy
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Vaccines
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Online Access:https://www.mdpi.com/2076-393X/13/3/224
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