Ketoins from Primary Alkylhalides, Grignard Compounds and Carbonmonoxide in Ether-HMPT

Whereas carbonylation of primary Grignard compounds in ether-HMPT leads to ketones 1, reaction in the presence of an additional amount of alkylhalide results in the formation of hydroxyketones 2 and 3. When using neat HMPT as solvent, 2 is the main product (up to 55 % yield).

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Bibliographic Details
Main Authors: W.J.J.M. Sprangers, A.P. van Swieten, R. Louw
Format: Article
Language:deu
Published: Swiss Chemical Society 1976-03-01
Series:CHIMIA
Online Access:https://www.chimia.ch/chimia/article/view/9303
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