Structural Insights into Mechanisms Underlying Mitochondrial and Bacterial Cytochrome c Synthases

Structural Insights into Mechanisms Underlying Mitochondrial and Bacterial Cytochrome c Synthases

Mitochondrial holocytochrome c synthase (HCCS) is an essential protein in assembling cytochrome c (cyt c) of the electron transport system. HCCS binds heme and covalently attaches the two vinyls of heme to two cysteine thiols of the cyt c CXXCH motif. Human HCCS recognizes both cyt c and cytochrome...

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Bibliographic Details
Main Authors: Pema L. Childs, Ethan P. Lowder, Deanna L. Mendez, Shalon E. Babbitt, Amidala Martinie, Jonathan Q. Huynh, Robert G. Kranz
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomolecules
Subjects:
heme
cytochrome c
heme attachment
cytochrome c synthase
structure
mechanisms
Online Access:https://www.mdpi.com/2218-273X/14/12/1483
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