Subtractive proteo-genomics and model-based druggability analyses prioritized nitrate reductase-A subunit-α as potential therapeutic target against MDR pneumonia; a homology-based approach
Abstract Background Bacterial pneumonia is a severe respiratory infection that damages the lungs, representing one of the most serious public health problems worldwide due to its morbidity and mortality across all age groups. The challenge is further exacerbated by emergence of multidrug-resistant s...
Saved in:
| Main Authors: | Kainat Begum, Sara Aiman, Asifullah Khan, Mah Noor Mumtaz, Fawad Ali, Shaik Althaf Hussain, Sara Khan, Mohammed Rafi Shaik |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
|
| Series: | BMC Microbiology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12866-025-03883-y |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Analysis of Mutations in Pneumocystis jirovecii Dihydropteroate Synthase and Dihydropteroate Reductase Genes Among Non-HIV Patients in China
by: Wu Y, et al.
Published: (2024-12-01) -
ASSESSING STROKE PATIENTS' TREATMENT AND PROGNOSIS TO ENHANCE THERAPEUTIC STRATEGIES
by: Nadeem Ullah Khan Wazir, et al.
Published: (2023-09-01) -
Subtractive genomics and drug repurposing strategies for targeting Streptococcus pneumoniae: insights from molecular docking and dynamics simulations
by: Borakha Bura Gohain, et al.
Published: (2025-03-01) -
The potential of methylethylpiridinol in treatment of bacterial infections caused by Klebsiella pneumoniae (experimental study)
by: V. M. Brykhanov, et al.
Published: (2016-10-01) -
Prediction model for severe mycoplasma pneumoniae pneumonia and analysis of macrolide-resistance in children: a case-control study
by: Shaoying Liu, et al.
Published: (2025-06-01)