The Effect of Carriage of <i>CYP3A5*3</i> and <i>CYP3A4*22</i> Polymorphic Variants on the Safety of Remdesivir Therapy in Patients with COVID-19

The Effect of Carriage of <i>CYP3A5*3</i> and <i>CYP3A4*22</i> Polymorphic Variants on the Safety of Remdesivir Therapy in Patients with COVID-19

The aim of the study was to assess the association of polymorphic variants CYP3A5*3 6986 A&gt;G rs776746 and CYP3A4*22 rs35599367 C&gt;T with the safety parameters of remdesivir therapy in patients with COVID-19.Material and methods. The study included 156 patients admitted to the City Clini...

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Main Authors: I. I. TEMIRBULATOV, A. V. KRYUKOV, K. B. MIRZAEV, N. P. DENISENKO, S. P. ABDULLAEV, A. S. ZHIRYAKOVA, Y. V. SHEVCHUK, V. I. VECHORKO, O. V. AVERKOV, D. A. SYCHEV
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2022-11-01
Series:Антибиотики и Химиотерапия
Subjects:
polymorphic gene variants
carriage
therapy safety
remdesivir
Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/947
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