Direct Activity Measurement of Heterotrimeric Gi Proteins and Gq Protein By Effector Pulldown

Studying G protein-coupled receptor (GPCR) activation of heterotrimeric G proteins is crucial for understanding diverse physiological processes and developing novel therapeutics. Traditional methods to assay GPCR activation of G proteins, including assays of second messengers and biosensors, involve...

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Bibliographic Details
Main Authors: Keiichiro Tanaka, Martin Schwartz
Format: Article
Language:English
Published: Bio-protocol LLC 2025-08-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=5406&type=0
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