QuEChERS and UPLC-MS/MS-Based Quantification of Human Plasma of Eight Nucleoside Reverse Transcriptase Inhibitors and Platinum Anticancer Drugs for Hepatocellular Carcinoma

QuEChERS and UPLC-MS/MS-Based Quantification of Human Plasma of Eight Nucleoside Reverse Transcriptase Inhibitors and Platinum Anticancer Drugs for Hepatocellular Carcinoma

Nucleoside reverse transcriptase inhibitors (NRTIs) and platinum-based chemotherapeutics are widely utilized in cancer treatment. Evidence suggests that drug plasma concentrations are closely linked to both therapeutic efficacy and the risk of adverse effects. Consequently, developing therapeutic dr...

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Bibliographic Details
Main Authors: Yanan Liu, Jiangning Peng, Yan Liang, Yilin Li, Xiaolan Zhen, Hui Li
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molecules
Subjects:
QuEChERS
UPLC-MS/MS
NRTIs
platinum
hepatocellular carcinoma
human plasma
Online Access:https://www.mdpi.com/1420-3049/30/10/2204
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